Oestrogen is one of the most important hormones in women’s health. It plays a vital role in regulating the menstrual cycle, supporting bone density, maintaining cardiovascular health, and influencing mood, skin health, and brain function.
However, when oestrogen is not adequately balanced by progesterone, it can lead to a hormonal pattern often referred to as oestrogen dominance. Despite how commonly the term is used online, oestrogen dominance is frequently misunderstood and oversimplified, because it isn’t a condition, it’s a description. Medical professionals will use more targeted language to describe what is going on with your body and hormones.
This article explains what oestrogen dominance really means, the symptoms to look out for, including acne, hot flushes and sleep disturbance, and how it is assessed and managed in a clinically safe way.
What Is Oestrogen Dominance?
When people use tthe phrase “oestrogen dominance”, what they are describing is the effects of oestrogen outweighing the balancing influence of progesterone. Importantly, this does not always mean that oestrogen levels are “high” on blood tests. In many cases, oestrogen levels may be normal or fluctuating, but progesterone levels are insufficient, creating a relative imbalance.
Progesterone plays a crucial role in:
- regulating the menstrual cycle
- calming the nervous system
- supporting sleep
- counteracting the stimulatory effects of oestrogen on the uterine lining
This imbalance is particularly common during perimenopause, when ovulation becomes irregular. As progesterone is produced only after ovulation, missed or inconsistent ovulation leads to falling progesterone levels, while oestrogen continues to fluctuate — often resulting in symptoms associated with a relative oestrogen dominance.
Common Causes of Oestrogen Dominance
Oestrogen dominance is influenced by a combination of hormonal changes, lifestyle factors, and environmental exposures.
Perimenopause and hormonal transition
Progesterone tends to decline earlier and more predictably than oestrogen during perimenopause, increasing the likelihood of imbalance.
Higher body fat levels
Adipose (fat) tissue produces oestrogen. Higher body fat can therefore contribute to increased circulating oestrogen.
Chronic stress
Long-term stress increases cortisol, which can suppress progesterone production and disrupt overall hormone balance.
Diet and lifestyle factors
Low fibre intake, excess alcohol, insulin resistance, ultra-processed foods and lack of movement can impair oestrogen metabolism and clearance.
Hormonal contraception or hormone therapy
Some women experience symptoms associated with oestrogen dominance when oestrogen is not adequately balanced with progesterone.
Symptoms of Oestrogen Dominance
Symptoms vary between individuals and often fluctuate throughout the menstrual cycle. Common features include:
- Heavy, painful or irregular periods
- Breast tenderness or swelling
- PMS or worsening premenstrual symptoms
- Mood swings, anxiety or irritability
- Headaches or hormonally triggered migraines
- Weight gain, particularly around hips and thighs
- Bloating and fluid retention
- Reduced libido
- Itchy skin/hives
Acne and Oestrogen Dominance
Acne can be a feature of oestrogen dominance, but it is usually indirect rather than caused by oestrogen alone.
In oestrogen-dominant states, progesterone is often low. Progesterone helps regulate oil production and balance androgen (testosterone-like) activity. When progesterone is insufficient:
- androgen effects can become more prominent
- sebaceous (oil) glands may become overactive
- pores are more likely to block, leading to acne
This often presents as hormonal-pattern acne, typically affecting the:
- jawline
- chin
- lower face and neck
Women may notice acne flaring:
- in the premenstrual (luteal) phase
- alongside PMS symptoms
- during perimenopause
It’s important to note that acne is not specific to oestrogen dominance and can also be caused by conditions such as PCOS, insulin resistance, stress, or hormonal changes after stopping contraception.
Hot Flushes and Night Sweats
Although hot flushes are often associated with low oestrogen, fluctuating or dominant oestrogen levels can also disrupt the brain’s temperature regulation. During perimenopause, unpredictable oestrogen surges and drops may trigger:
- sudden feelings of heat
- flushing
- sweating
- night sweats
Some women notice that hot flushes worsen during periods of hormonal imbalance rather than improving with higher oestrogen levels alone.
Sleep Disturbance
Progesterone has a calming, sleep-promoting effect on the nervous system. When progesterone levels are low relative to oestrogen, women may experience:
- difficulty falling asleep
- frequent night waking
- vivid dreams
- early morning waking
- sleep disruption due to night sweats
Poor sleep can then worsen stress hormones and further disrupt hormonal balance, creating a vicious cycle.
Health Risks of Prolonged Oestrogen Dominance
If left unaddressed, ongoing oestrogen dominance — particularly unopposed oestrogen — may increase the risk of:
- Endometrial hyperplasia and endometrial cancer
- Worsening fibroids or endometriosis
- Increased lifetime exposure to oestrogen, linked to breast cancer risk
- Bone density changes during the menopausal transition
- Possible cardiovascular effects in susceptible individuals
This is why persistent symptoms should always be properly assessed rather than self-treated.
How Is Oestrogen Dominance Managed?
Management should always be individualised and based on symptoms, life stage, medical history and risk factors.
Lifestyle and nutrition
A fibre-rich diet with plenty of vegetables (especially cruciferous vegetables), adequate protein and healthy fats supports oestrogen metabolism. Reducing alcohol and ultra-processed foods is also beneficial.
Stress management
Addressing chronic stress through realistic lifestyle changes, gentle movement, mindfulness or support can significantly improve hormone balance.
Exercise
Regular movement helps regulate insulin, reduce excess body fat and support healthy hormone clearance.
Targeted supplementation
Some women benefit from magnesium, vitamin B6, omega-3 fatty acids or liver-supportive nutrients. Supplements should be tailored and clinically guided.
Hormonal treatment
In some cases, prescribed progesterone or carefully balanced hormone therapy may be appropriate, particularly during perimenopause or menopause. This should always be personalised and reviewed regularly.
When to Seek Medical Advice
You should seek medical advice if you experience:
- heavy or irregular bleeding
- worsening PMS or mood symptoms
- persistent acne with other hormonal features
- hot flushes or night sweats
- ongoing sleep disruption
Hormonal symptoms overlap with many conditions, and proper assessment ensures safe and effective treatment.
Frequently Asked Questions (FAQ)
What is oestrogen dominance?
Oestrogen dominance refers to a hormonal imbalance where the effects of oestrogen outweigh those of progesterone. This does not always mean oestrogen levels are high; it is often due to low or insufficient progesterone, particularly during perimenopause when ovulation becomes irregular.
Is oestrogen dominance a recognised medical condition?
“Oestrogen dominance” is not a formal diagnostic label used in guidelines, but it is a useful clinical concept to describe a common hormonal pattern seen in women with symptoms related to relative progesterone deficiency and fluctuating oestrogen, especially in perimenopause.
What are the most common symptoms of oestrogen dominance?
Symptoms vary but commonly include:
- Heavy or irregular periods
- PMS or worsening premenstrual symptoms
- Breast tenderness
- Bloating and fluid retention
- Mood swings or anxiety
- Hormonal headaches or migraines
- Weight gain around hips and thighs
- Acne (particularly jawline and chin)
- Hot flushes and night sweats
- Poor or disrupted sleep
Can oestrogen dominance cause acne?
Yes, acne can be a feature of oestrogen dominance, but usually indirectly. Low progesterone allows androgen effects to become more prominent, increasing oil production in the skin. This often causes hormonal-pattern acne, particularly on the jawline, chin and lower face. Acne should always be assessed in context, as it can have multiple causes.
Can oestrogen dominance cause hot flushes?
Yes. While hot flushes are often associated with low oestrogen, hormonal fluctuation and imbalance — including oestrogen dominance — can disrupt temperature regulation in the brain, particularly during perimenopause.
Does oestrogen dominance affect sleep?
Very commonly. Progesterone has a calming effect on the nervous system and supports sleep. When progesterone is low relative to oestrogen, women may experience difficulty falling asleep, frequent night waking, vivid dreams or sleep disruption due to night sweats.
Is oestrogen dominance the same as perimenopause?
Not exactly. Perimenopause is a life stage, whereas oestrogen dominance describes a hormonal pattern that commonly occurs during perimenopause. Many women in perimenopause experience periods of oestrogen dominance due to declining progesterone.
How is oestrogen dominance diagnosed?
There is no single test that diagnoses oestrogen dominance. Diagnosis is based on:
- symptoms
- menstrual history
- life stage
- medical history
- targeted blood tests where appropriate
Symptoms and clinical context are often more informative than hormone levels alone.
How is oestrogen dominance treated?
Treatment is individualised and may include:
- lifestyle and dietary changes
- stress management
- targeted supplementation
- hormonal treatment (such as progesterone or balanced HRT) where appropriate
Management should always be guided by a healthcare professional.
When should I seek medical advice?
You should seek medical advice if you experience persistent symptoms such as heavy bleeding, significant mood changes, worsening acne, hot flushes, or ongoing sleep disruption, particularly if symptoms affect your quality of life.
Final Thoughts
Oestrogen dominance is a common but often misunderstood hormonal pattern, particularly during perimenopause. It can affect many areas of health — including mood, periods, skin, sleep and temperature regulation — but it is manageable with the right support.
Understanding your hormones is a powerful step towards feeling more confident and in control of your health. With personalised care, symptoms can improve and long-term risks can be reduced.
Further Reading
The following organisations provide evidence-based, medically reviewed information on hormones, perimenopause and menopause:
- National Institute for Health and Care Excellence (NICE) – Menopause: Diagnosis and Management (NG23)
https://www.nice.org.uk/guidance/ng23 - British Menopause Society
https://thebms.org.uk/ - Women’s Health Concern
https://www.womens-health-concern.org/ - Royal College of Obstetricians and Gynaecologists
https://www.rcog.org.uk/for-the-public/ - Endocrine Society
https://www.endocrine.org/patient-engagement